Archive for May 28th, 2010
Magnesium Supplements to help prevent coronary artery disease.
In the United States, the most common type of heart disease and the leading cause of death is coronary heart disease also known as coronary artery disease (CAD). Coronary artery disease occurs when a substance called plaque builds up in the arteries that supply blood to the heart (called coronary arteries). Plaque is made up of cholesterol deposits, which can accumulate in your arteries. When this happens, your arteries can narrow over time. This process is called atherosclerosis. Plaque buildup can cause angina, the most common symptom of CAD. This condition causes chest pain or discomfort because the heart muscle doesn’t get enough blood. Over time, CAD can weaken the heart muscle. This may lead to heart failure, a serious condition where the heart can’t pump blood the way that it should. An irregular heartbeat, or arrhythmia, can also develop. For some people, the first sign of CAD is a heart attack. A heart attack occurs when plaque totally blocks an artery carrying blood to the heart. It also can happen if a plaque deposit breaks off and clots a coronary artery. Magnesium is a cofactor in over 300 enzymatic reactions in the body. It is necessary for the transmission of nerve impulses, muscular activity, temperature regulation, detoxification reactions, and for the formation of healthy bones and teeth. It is involved in energy production and the synthesis of DNA and RNA. A
U.S. Department of Agriculture survey revealed that approximately 75 percent of Americans do not ingest the RDA of magnesium. Sub-optimal magnesium intake compromises cellular activity, especially in tissues of the heart, nerves, and kidneys. Magnesium influences many of the activities associated with a wide variety of cardiac medications. For example, magnesium inhibits platelet aggregation, thins the blood, blocks calcium uptake (like calcium channel blocking drugs), and relaxes blood vessels (like ACE inhibitors). Magnesium also increases oxygenation of the heart muscle by improving cardiac contractility. A study conducted at Brigham Young University, Provo, Utah was published in the Journal of the American Academy of Nurse Practitioners. The scientists found six randomized control clinical trials and prospective studies that met their criteria for the study which was to investigate the safety and efficacy of magnesium supplements in patients with coronary heart disease or patients at risk for the disease. Magnesium dosages ranged from 130 to 800 milligrams per day. The results were a higher magnesium intake was associated with reduced risk of CHD in male subjects but there was no decrease in the development of CHD in women who also had a high magnesium intake. There were no adverse effects reported. The researchers suggested that “There is a possible association between a modestly lower risk of CHD in men and increased magnesium intake; therefore, it is reasonable to encourage diets high in magnesium as a potential means to lower the risk of CHD
